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Two Cases of Multiple Eccrine Spiradenoma with Linear or Localized Formation
Author(s) -
Yoshida Aki,
Sato Toshiki,
Sugawara Yuki,
Matsuta Mayumi,
Akasaka Toshihide
Publication year - 2004
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.2004.tb00556.x
Subject(s) - chin , eosinophilic , homogeneous , nodule (geology) , pathology , cytoplasm , medicine , soft tissue , anatomy , biology , paleontology , biochemistry , physics , thermodynamics
We report two rare cases of recurrent, multiple eccrine spiradenoma. Both cases presented with extensive lesions comprised of multiple red papules of various sizes and a soft blue‐red nodule. The first case was a 30‐year‐old woman. Her lesions followed a linear arrangement on her chin, and extended down the right side of the neck with spontaneous pain. The second case was a 57‐year‐old woman with tumors in a localized group on the left occipital region without pain. A search of the literature revealed only 15 reported cases of linear/zosteriform/nevoid multiple eccrine spiradenoma. Both cases were treated by surgical excision. Most of the red papules displayed typical histological features including two cell types: large clear cells with low‐density cytoplasm; and small dark cells with high‐density cytoplasm. The large soft tumors exhibited a variable histological appearance. In the first case, the cystic tumors displayed an homogeneous structure comprised of eosinophilic material. In the second case, the cystic tumors included abundant interstitial tissue.