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Recalcitrant Oral Pyoderma Gangrenosum in a Child Responsive to Cyclosporine
Author(s) -
Park HyangJoon,
Han BongGyun,
Kim YouChan,
Cinn YongWoo
Publication year - 2003
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.2003.tb00444.x
Subject(s) - pyoderma gangrenosum , tongue , medicine , histopathology , lesion , dermatology , prednisolone , eosinophilia , pathology , disease , surgery
We report a case of recalcitrant pyoderma gangrenosum which developed on the tongue of an 8‐year‐old, previously healthy boy without any systemic associated disease. The lesion was confined to the tongue and was not responsive to conventional treatment with prednisolone and sulfa drug, but it showed dramatic improvement with oral cyclosporine therapy. In addition, the histopathology of the lesion included many eosinophils, which caused difficulties in diagnosis to differentiate this condition from other oral ulcerative diseases showing tissue eosinophilia including eosinophilic ulcer of the tongue.