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Pentoxifylline in the Treatment of Erythema Nodosum Leprosum
Author(s) -
Carsalade GeorgesYves,
Achirafi Aboubacar,
Flageul Béatrice
Publication year - 2003
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.2003.tb00335.x
Subject(s) - pentoxifylline , medicine , leprosy , thalidomide , dermatology , lepromatous leprosy , erythema nodosum , pharmacology , immunology , disease , multiple myeloma
Erythema nodosum leprosum (ENL) is a well‐known serious complication affecting 10% of lepromatous multibacillary leprosy patients. In the chronic form, its morbidity may be considerable. Thalidomide and systemic steroids are the two current effective drugs for the management of ENL. However, their use in endemic countries is often difficult and hazardous, and a search for new therapies is needed. We report our experience on the effects of pentoxifylline, a methylxanthine derivative, which has recently been suggested as a possible effective treatment for ENL attacks.