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Bullous Pyoderma Gangrenosum Complicated by Disseminated Intravascular Coagulation with Subsequent Myelodysplastic Syndrome (Chronic Myelomonocytic Leukemia)
Author(s) -
Rogalski Christina,
Paasch Uwe,
Glander HansJürgen,
Haustein UweFrithjof
Publication year - 2003
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.2003.tb00334.x
Subject(s) - chronic myelomonocytic leukemia , disseminated intravascular coagulation , medicine , pyoderma gangrenosum , leukemia , dermatology , myelodysplastic syndromes , pathology , immunology , bone marrow , disease
A 33‐year‐old woman developed a bullous PG precursing a chronic myelomonocytic leukemia (CMML) complicated by life‐threatening, disseminated, intravascular coagulation after administration of systemic corticosteroids in combination with immunosuppressant and antibiotic agents. Although the association between PG and leukemia, as well as the coincidence of disseminated intravascular coagulation (DIC) and leukemia, is well known, a premonitoring effect of PG in combination with DIC preceding the diagnosis of chronic myelomonocytic leukemia in the same patient has not been reported recently.