Premium
Unilateral Generalized Morphea in Childhood
Author(s) -
Nagai Yayoi,
Hattori Tomoyasu,
Ishikawa Osamu
Publication year - 2002
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.2002.tb00301.x
Subject(s) - morphea , medicine , dermis , anti nuclear antibody , trunk , deformity , skin biopsy , upper trunk , thigh , dermatology , biopsy , pathology , surgery , antibody , autoantibody , biology , ecology , brachial plexus , immunology
We report a 6‐year‐old boy with unilateral generalized morphea distributing on the right side of his lower leg, trunk, and upper arm. A skin biopsy from the right thigh showed accumulation of thick collagen bundles extending from the middle dermis to the subcutaneous fat tissue. The levels of antinuclear antibodies, rheumatoid factor, and anti single‐stranded DNA antibody were elevated. No severe deformity or functional disabilities were noted. With topical corticosteroid therapy, the sclerotic skin became gradually softer, and no progression of sclerosis has been noted for one year.