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A Case of Cutaneous Ganglioneuroma Developing within a Lesion of Seborrheic Keratosis
Author(s) -
Ohno Sayoko,
Horiguchi Yuji,
Shintaku Masayuki
Publication year - 2002
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.2002.tb00267.x
Subject(s) - seborrheic keratosis , lesion , ganglioneuroma , medicine , pathology , granulation tissue , eosinophilic , dermatology , biology , surgery , neuroblastoma , wound healing , genetics , cell culture
Abstract A 67‐year‐old man noticed on the abdominal skin a coin‐sized verrucous plaque, in which a small granulation‐like lesion developed several weeks before the first consultation at our clinic. The histology of the biopsied granulation‐like lesion showed a well demarcated, but not associated with the collagenous capsule, mass of proliferating eosinophilic cells, consisting of intervening spindle‐shaped Schwann cells and mature ganglion cells scattered in the tumor nest. We diagnosed this tumor nest as a ganglioneuroma, which rarely develops in the skin tissue. The simply resected surrounding verrucous lesion was histologically seborrheic keratosis.