Premium
Report of Eight Infants with Acute Infantile Hemorrhagic Edema and Review of the Literature
Author(s) -
Çaksen Hüseyin,
Odabaş Dursun,
Kösem Mustafa,
Arslan Şükrü,
Öner Ahmet Faik,
Ataş Bülent,
Akçay Gürbüz,
Ceylan Nesrin
Publication year - 2002
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.2002.tb00265.x
Subject(s) - medicine , leukocytoclastic vasculitis , purpura fulminans , purpura (gastropod) , edema , dermatology , differential diagnosis , vasculitis , surgery , pathology , disease , ecology , biology
Acute infantile hemorrhagic edema (AIHE) is a cutaneous leukocytoclastic vasculitis, clinically characterized by the symptom triad of fever, large purpuric skin lesions, and edema. The clinical picture has a violent onset, a short benign course, and spontaneous complete recovery. In this article, we present eight patients who were admitted with rashes on the skin and edema on the eyelids and extremities, and were diagnosed with AIHE according to their clinical and histopathological features (immunohistological study was also performed in three of them). Our purpose was to emphasize that, aside from Henoch‐Schönlein purpura, meningococcemia, septicemia, and purpura fulminans, AIHE benign disorder should also be considered in the differential diagnosis to determine the clinical course and treatment protocol in patients with purpuric rashes.