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A Case of Primary Cutaneous Histoplasmosis in a Patient with Diabetes and Multi‐Infarct Dementia
Author(s) -
Krunic Aleksandar L.,
Carag Henry,
Medenica Maria M.,
Lorincz Allan L.
Publication year - 2002
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.2002.tb00226.x
Subject(s) - histoplasmosis , medicine , forehead , clearance , itraconazole , dementia , diabetes mellitus , dermatology , biopsy , skin biopsy , surgery , pathology , disease , antifungal , urology , endocrinology
We report a case of primary cutaneous histoplasmosis in a fifty‐year‐old African‐American woman with diabetes and multi‐infarct dementia. The patient developed fever and crusted, nodulo‐ulcerative lesions of the skin after accidental superficial trauma to the forehead. The biopsy revealed suppurative granulomatous inflammation with intracellular and extracellular yeast‐like cells with associated clear halo measuring 3–4 μm in size. Systemic involvement was not found. The lesions cleared after treatment with itraconazole 200 mg twice a day for 3 weeks. The medication was continued for a total period of 3 months, with no signs of recurrence after one‐year of follow‐up.