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Hair Follicle Nevus Occurring in Frontonasal Dysplasia: An Electron Microscopic Observation
Author(s) -
Kuwahara Hiroaki,
Lao LiMin,
Kiyohara Takahiro,
Kumakiri Masanobu,
Igawa Hiroharu
Publication year - 2001
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.2001.tb00142.x
Subject(s) - vellus hair , dermis , pathology , hair follicle , anatomy , stroma , lesion , biology , medicine , endocrinology , immunohistochemistry , scalp
We report a rare hair follicle nevus that occurred in a three‐month‐old Japanese boy with mild frontonasal dysplasia. It had been present since birth. Histologically, numerous tiny vellus hair follicles were found within the dermis. The constituent cells of these follicles showed the features of follicular germ cells under the electron microscope. The fibroblasts around the follicles were active and merged with the colloid substance. Many myofibroblasts were found in a collagenous stroma in the atrophic lesion of the frontonasal dysplasia.