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A Case of Lichenoid Purpura Possibly Caused by Diltiazem Hydrochloride
Author(s) -
Inui Shigeki,
Itami Satoshi,
Yoshikawa Kunihiko
Publication year - 2001
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.2001.tb00098.x
Subject(s) - diltiazem hydrochloride , dermoepidermal junction , purpura (gastropod) , medicine , histiocyte , infiltration (hvac) , diltiazem , pathological , dermatology , biopsy , pathology , dermis , ecology , alternative medicine , physics , biology , thermodynamics
A 65‐year‐old Japanese man presented with itchy purpuric lichenoid papules of six months' duration on his legs and buttock. A topical glucocorticoid ointment was not effective. The biopsy specimen histologically showed a dense lichenoid infiltration of lymphocytes and histiocytes into the dermoepidermal junction; red blood cells were seen in the infiltration. Based on the clinical and pathological findings, we diagnosed this case as lichenoid purpura of Gougerot‐Blum. The lesions disappeared when the diltiazem hydrochloride that he had been taking was discontinued.