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Erythematous Swelling of the Lip Associated with Sjögren's Syndrome and Mimicking Cheilitis Granulomatosa
Author(s) -
Fujimura Taku,
Aiba Setsuya,
Suetake Takaki,
Tagami Hachiro
Publication year - 2001
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.2001.tb00086.x
Subject(s) - medicine , erythema , dermis , infiltration (hvac) , pathology , swelling , dermatology , physics , thermodynamics
A 64‐year‐old Japanese woman developed therapy‐resistant erythematous swelling of her upper lip. Our tentative clinical diagnosis of cheilitis granulomatosa was ruled out later by the laboratory findings including increased levels of anti‐nuclear‐antibody (ANA), anti‐SS‐A/Ro antibody, and positive Schirmer test as well as by a histopathological picture showing a dense perivascular infiltration of plasma cells and mononuclear cells in the dermis instead of granulomatous changes. To the best of our knowledge, this is the first patient in whom annular erythema associated with Sjögren's syndrome involved only the upper lip and produced clinical features simulating cheilitis granulomatosa.