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Leukocytoclastic Vasculitis with IgA Deposits in Angioimmunoblastic T Cell Lymphoma
Author(s) -
Sugaya Makoto,
Nakamura Koichiro,
Asahina Akihiko,
Tamaki Kunihiko
Publication year - 2001
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.2001.tb00083.x
Subject(s) - purpura (gastropod) , medicine , angioimmunoblastic t cell lymphoma , lymphoma , pathology , leukocytoclastic vasculitis , vasculitis , lymph node , virus , palpable purpura , histology , henoch schonlein purpura , immunology , disease , t cell , biology , immune system , ecology
Angioimmunoblastic T cell lymphoma (AILD) is a type of peripheral T cell lymphoma associated with fever and generalized lymphadenopathy. Cutaneous manifestations are seen in approximately 40% of the patients. We report herein a Japanese male patient with AILD associated with generalized purpura. The histology of the purpura included leukocytoclastic vasculitis with IgA deposits, which is rare in this disease. Using in situ hybridization and PCR methods, we showed that the involved lymph node was positive for Epstein‐Barr virus and that the purpura was negative.