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Rod‐shaped Bodies Resembling Birbeck Granule‐like Structures in Endothelial Cells of Dermal Capillaries in Generalized Granuloma Annulare
Author(s) -
Kohn Sarah,
FriedmanBirnbaum Rachel
Publication year - 2001
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.2001.tb00078.x
Subject(s) - birbeck granules , granuloma annulare , pathology , granule (geology) , anatomy , langerhans cell , biology , medicine , immunology , immune system , paleontology
A previous study demonstrated that, in generalized granuloma annulare in the epidermis, the Langerhans' cell section area and the number of Langerhans' cell granules or Birbeck granules per cell section were increased, suggesting an active state of these Langerhans' cells. Reexamination by transmission electron microscopy of the same tissue, but in samples also containing dermal tissue, from the same subjects revealed endothelial cells with rod‐shaped bodies resembling Birbeck granules or Birbeck granule‐like structures. This finding has not been previously described in blood vessels of human skin and is described here.