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Pedunculated Melanoma with Pulmonary and Bony Metastases
Author(s) -
Kato Naoko,
Kimura Kumiko,
Sugawara Hiroshi,
Aoyagi Satoru,
Kondo Keishi,
Yamashiro Katsushige
Publication year - 2000
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.2000.tb02279.x
Subject(s) - melanoma , medicine , metastasectomy , nodule (geology) , dermis , metastatic melanoma , lymph , epidermis (zoology) , lung , pathology , nevus , epithelioid cell , metastasis , anatomy , immunohistochemistry , cancer , biology , cancer research , paleontology
We report a patient with pedunculated melanoma. Rounded and epithelioid‐type melanoma cells had proliferated in the epidermis and massively into the deep dermis in the pedunculated nodule. At the base of the pedicle, lengtiginous‐type melanoma cells formed nests of various sizes in the epidermis extending ten or more rete ridges beyond the site of invasion. Thus, this case shows that a pedunculated melanoma is not necessarily a variant of nodular melanoma. Six years after the primary operation, late recurrence was detected in regional lymph nodes, and nine years after the initial operation, the patient was found to have three large metastatic nodules, up to 8.5 cm in longest diameter, in her lung and bone. Although she died six months after the metastasectomy, prompt surgical excision of the primary tumor and metastasectomy can provide longer survival.