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Postoperative Hyponatremia in a Patient with ACTH‐Producing Merkel Cell Carcinoma
Author(s) -
Anzai Saburo,
Sato Toshihiro,
Takayasu Susumu,
Asada Yuji,
Terashi Hiroto,
Takasaki Syuji
Publication year - 2000
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.2000.tb02190.x
Subject(s) - merkel cell carcinoma , hyponatremia , medicine , merkel cell , carcinoma , neuroendocrine carcinoma , pathology
Merkel cell carcinoma is characterized by specific neuroendocrine features and the expression of several neuropeptides. We report a case of Merkel cell carcinoma with post‐surgical hyponatremia in an 85‐year‐old Japanese woman. A tumor on the left cheek histopathologically showed the characteristics of Merkel cell carcinoma together with Bowen's disease. Although an increased level of ACTH was found both in the tumor and in the peripheral blood, the postoperative hyponatremia in our patient seems more likely to have been caused by the stress of the operation and indapamide, considering that the ACTH level in the tumor was much lower than those in other ectopic ACTH‐producing tumors in previous reports.