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Hyalinizing Spitz Nevus
Author(s) -
Lee MiWoo,
Choi JeeHo,
Sung KyungJeh,
Moon KeeChan,
Koh JaiKyoung
Publication year - 2000
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.2000.tb02164.x
Subject(s) - spitz nevus , pathology , vimentin , nevus , dermatology , cytokeratin , immunohistochemistry , cd68 , medicine , melanoma , cancer research
A seventeen‐year‐old Korean girl had a reddish‐brown papular lesion on the nose. Histopathologically, it proved to be a “hyalinizing Spitz nevus” with the characteristic features of a discohesive growth pattern of nevus cells and hyalinized stroma. Immunohistochemical stains showed positive reactivity of nevus cells with S‐100 protein and Vimentin and negative stainings with HMB45, CD68, CEA and low molecular weight cytokeratin. Hyalinizing Spitz nevus may represent a variant in the spectrum of Spitz nevus.