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A Case of Combined Nevus: Compound Nevus and Spindle Cell Spitz Nevus
Author(s) -
Jin Zhaohui,
Kumakiri Masanobu,
Ishida Hisaya,
Kinebuchi Shoichi
Publication year - 2000
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.2000.tb02157.x
Subject(s) - nevus , spitz nevus , nodule (geology) , atypia , medicine , pathology , lesion , dermatology , anatomy , melanoma , biology , cancer research , paleontology
Combined nevi consisting of a Spitz nevus and an acquired nevus are unusual, and, to our knowledge, the combination of a spindle cell Spitz nevus and an overlying compound nevus has not been previously reported. We report a 17‐year‐old girl with a nodule on the left anterior lower extremity. The nodule was asymptomatic, firm, brown, symmetrical, dome‐shaped, 8 mm in diameter, and not found with ulceration. Histological findings showed proliferation of spindle‐shaped cells with an overlying compound nevus. The spindle‐shaped cells were large, non‐pigmented, uniform in size and shape, with rare mitoses and without nuclear atypia, and arranged in a storiform pattern in thick collagen bundles. They stained positively for S‐100 and negatively for HMB‐45. The lesion was considered to be a new type of combined nevus consisting of a spindle cell Spitz nevus and an overlying compound nevus.