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Pseudolymphoma Syndrome due to Carbamazepine
Author(s) -
Saeki Hidehisa,
Etoh Takafumi,
Toda Kiyoshi,
Mihm Martin C.
Publication year - 1999
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.1999.tb03480.x
Subject(s) - pseudolymphoma , carbamazepine , pathology , medicine , lymphoma , histology , histopathological examination , dermatology , epilepsy , psychiatry
We described a 29‐year‐old Japanese woman with a pseudolymphoma syndrome due to carbamazepine. Physical examination revealed a diffuse erythematous papular eruption over almost all of her body with generalized lymphadenopathy. Histopathologic examination disclosed histology compatible with the nodular pattern of pseudo‐T‐cell lymphoma. The Southern blot analysis did not disclose the monoclonality of the gamma T cell recepter gene. We consider that it is very important to recognize this pseudolymphoma syndrome due to carbamazepine to avoid possibly subjecting the patient to unnecessary chemotherapy.