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Epstein‐Barr Virus‐Associated Lymphoproliferative Skin Lesion with Recurrent Necrotic Papulovesicles of the Face
Author(s) -
Jung Doo Yeoul,
Kim Ji Won,
Lee Sook Kyung,
Lee Won Woo
Publication year - 1999
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.1999.tb02024.x
Subject(s) - scars , lesion , erythema , skin lesion , pathology , medicine , virus , lymphoproliferative disorders , necrosis , dermatology , immunology , lymphoma
A 24‐year‐old man showed recurrent necrotic papulovesicles of the face. The cutaneous lesions started with erythema, followed by vesicles, necrosis, and crusting, and leaving depressed scars. Light avoidance did not prevent the development of the lesions. Histologic examination revealed lymphoproliferative lesions confined to the skin. Latent Epstein‐Barr virus (EBV) infection was detected in the lymphoid cells from the skin lesions by in situ hybridization. A moderate to high dosage of corticosteroids suppressed the development of new skin lesions, but relapses occurred when these systemic corticosteroids were tapered.