Premium
Verruca Vulgaris Developing during Cyclosporin Therapy for Psoriasis Vulgaris
Author(s) -
Irimajiri Junya,
Yamamoto Toshiyuki,
Kimura Kyoko,
Yokozeki Hiroo,
Nishioka Kiyoshi
Publication year - 1998
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.1998.tb02483.x
Subject(s) - verruca vulgaris , medicine , scalp , psoriasis , dermatology , nodule (geology) , ciclosporin , surgery , chemotherapy , biology , paleontology
Several kinds of side effects have recently been reported with cyclosporin (CsA) therapy. We describe two patients with psoriasis vulgaris who developed verrucae vulgaris during systemic CsA therapy. In one case, a verrucous nodule appeared on the scalp and grew rapidly in a 54‐year‐old male with psoriasis vulgaris 29 months after starting CsA therapy. The total dose of CsA was 87.5 g, and average dose of CsA was 2 mg/kg/day. In the other case, multiple verrucae vulgaris developed on the scalp, face, knee, and inguinal region in a 54‐year‐old male. He had been given CsA for 10 months, the total dose was 45.5 g, and the average dose was 3 mg/kg/day. He also had Sjögren's syndrome. Most of the verrucae vulgaris lesions spontaneously disappeared after stopping the CsA.