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Pemphigus Vulgaris Associated with Transient Acanthosis Nigricans Like Lesion
Author(s) -
Usui Keitaro,
Kondo Aki,
Nakagawa Hidemi
Publication year - 1998
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.1998.tb02454.x
Subject(s) - pemphigus vulgaris , acanthosis nigricans , dermatology , acanthosis , medicine , lesion , skin lesion , pemphigus , pathology , hyperkeratosis , insulin resistance , obesity
A patient with pemphigus vulgaris was treated with predonisolone and cyclosporin. At the sites of healing erosions, hyperkeratotic, hyperpigmented plaques developed; they were clinically and histologically similar to acanthosis nigricans. These lesions regressed after a few months. This case and others described in the literature suggest that such dermatoses might be caused by immunologically as well as mechanically mediated epidermal injury.