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The Discrepancy in Hardness between Clinical and Histopathological Findings in Localized Scleroderma Treated with PUVA
Author(s) -
Yamaguchi Keiko,
Takeuchi Izuho,
Yoshii Noriko,
Gushi Akira,
Kanekura Takuro,
Kanzaki Tamotsu
Publication year - 1998
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.1998.tb02452.x
Subject(s) - scleroderma (fungus) , puva therapy , medicine , dermatology , localized scleroderma , pathology , psoriasis , lichen sclerosus , inoculation
Topical PUVA therapy was applied to a patient with localized scleroderma. Her localized scleroderma responded very well to the topical PUVA therapy, i.e. , her sclerotic skin softened to normal skin texture. However, despite this dramatic clinical change the histopathological findings did not change at all and were still “hard”.