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Is the Heredity of Reticulate Acro Pigmentation of Kitamura always Autosomal Dominant?
Author(s) -
Singal Archana,
Bhattacharya Sambit Nath,
Baruah Manik Chand,
Indrayan Abhay,
Singh Navjeevan
Publication year - 1998
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.1998.tb02348.x
Subject(s) - reticulate , heredity , inheritance (genetic algorithm) , genetics , autosomal recessive inheritance , biology , dermatology , evolutionary biology , medicine , botany , gene
Reticulate acropigmentation of Kitamura (RAK) in three patients and their families is described. In one family, 2 women and 2 men were affected out of 9 individuals. In the other family, 6 women had lesions of reticulate acropigmentation out of total of 27 over three generations. In the third family, one man was affected. All of the cases had palmar pits; onset of lesions was after puberty in all the cases. The apparently different hereditary patterns in these three families are striking, and autosomal dominant inheritance appears unlikely in every case.