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Merkel Cell Carcinoma: Report of Three Cases
Author(s) -
Okamoto Osamu,
Yoshiyama Masako,
Takayasu Susumu,
Yokoyama Shigeo
Publication year - 1998
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.1998.tb02345.x
Subject(s) - merkel cell carcinoma , carcinoma , cancer research , pathology , medicine
Three cases of Merkel cell carcinoma are reported: Case 1 on the upper eyelid with regional lymph node metastasis, Case 2 with spontaneous regression after repeated biopsies, and Case 3 presumably developing on the lesion of pre‐existing Bowen's disease. In Case 2, the biopsy specimen was characterized by numerous apoptotic cells in the periphery of the tumor nests surrounded by lymphocytic infiltration. In Case 3, the tumor developed after injury to the pre‐existing lesion of Bowen's disease.