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A Case of Lyme Disease Diagnosed Serologically
Author(s) -
Fujita Hiroshi,
Ogusu Koji,
Imaizumi Shunsuke,
Masuzawa Toshiyuki,
Yanagihara Yasutake
Publication year - 1997
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.1997.tb02773.x
Subject(s) - erythema migrans , borrelia , lyme disease , flagellin , erythema , minocycline , medicine , blot , kilodalton , spirochaetaceae , monoclonal antibody , neuroborreliosis , borrelia burgdorferi , dermatology , immunology , virology , biology , antibody , microbiology and biotechnology , antibiotics , lyme borreliosis , biochemistry , receptor , gene
A 57‐year‐old Japanese male developed erythema migrans, arthralgia, and neurological symptoms after mountain climbing in Nagano Prefecture. On ELISA, his serum reacted to Borrelia isolated from various sources. The patient's serum reacted with a 41 kilodalton protein which was reactive with monoclonal antibody H9724 specific to flagellin of Borrelia on Western blotting. He recovered after taking minocycline 200 mg daily for 2 weeks.