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Evaluation of Acceleration Plethysmograms in Dermatology—Efficacy of Lipo PGE 1 Preparations against Herpes Zoster and Neuralgia Following Herpes
Author(s) -
Okuda Tomoki,
Ohi Tsunao,
Koga Michiyuki
Publication year - 1997
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.1997.tb02320.x
Subject(s) - medicine , anesthesia , neuralgia , analgesic , significant difference , pulse rate , hemodynamics , neuropathic pain , blood pressure
Reports published in recent years indicate that administration of lipo PGE 1 is effective against herpes zoster and neuralgia following herpes. However, there are presently no standards to objectively assess efficacy. We therefore looked into the possibility of achieving this goal by using an acceleration plethysmograph. The results showed a significant difference in the rate of change of pulse waves after initiation of drip infusion as compared to before drip infusion among the effective group, the control group, and the non‐effective group. This method appears to be useful to objectively assess both the analgesic effects of lipo PGE 1 and the efficacy of drugs in general, based on data analysis. Our results suggest that investigations using this method may be able to predict the therapeutic effects of vasodilators and analyze hemodynamic disorders of the skin.