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Successful Treatment of Scleroderma with PUVA Therapy
Author(s) -
Kanekura Takuro,
Fukumaru Seita,
Matsushita Shigeto,
Terasaki Kenjiro,
Mizoguchi Shimako,
Kanzaki Tamotsu
Publication year - 1996
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.1996.tb04054.x
Subject(s) - puva therapy , scleroderma (fungus) , dermatology , medicine , psoriasis , pathology , inoculation
PUVA therapy was carried out on four patients with scleroderma; three of them had cutaneous manifestations of progressive systemic sclerosis and one other exhibited generalized morphea. PUVA therapy was given with daily doses of 0.25 J/cm 2 or 0.4 J/cm 2 for 3–8 weeks, resulting in total doses between 3.5 J/cm 2 and 9.6 J/cm 2 . All four patients responded well to this treatment; improvements of hand closure, skin sclerosis index, and flexion of fingers or knee joints were obtained. Thus, PUVA appeared to be beneficial for treating scleroderma.