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Progressive Systemic Sclerosis Sine Scleroderma which Developed after Exposure to Epoxy Resin Polymerization
Author(s) -
Inachi Shin,
Mizutani Hitoshi,
Ando Yoko,
Shimizu Masayuki
Publication year - 1996
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.1996.tb04028.x
Subject(s) - scleroderma (fungus) , morphea , progressive systemic sclerosis , medicine , epoxy , telangiectasia , dermatology , hyperpigmentation , systemic scleroderma , pathology , raynaud disease , biopsy , materials science , composite material , inoculation , dermatomyositis
Progressive systemic sclerosis (PSS) sine scleroderma is well known as a special form of scleroderma. Because of its rarity, its pathogenesis has not yet been elucidated. We experienced a 33‐year‐old man who developed PSS sine scleroderma while working with epoxy resin polymerization. He had short white frenulum linguae, diffuse hyperpigmentation and facial telangiectasia, positive antinuclear antibody, and pulmonary dysfunction, but not acrosclerosis or sclerodactylia. Modest dermal collagen proliferation in the forearm skin confirmed PSS sine scleroderma. Epoxy resin polymerizer appears to be a potent causative agent for PSS sine scleroderma as well as for generalized morphea‐like PSS.