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Giant Basal Cell Carcinoma Associated with Systemic Amyloidosis
Author(s) -
Yamamoto Shinji,
Johno Masayoshi,
Kayashima Kenichi,
Matsunaga Wakatoshi,
Ono Tomomichi
Publication year - 1996
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.1996.tb04025.x
Subject(s) - medicine , basal cell carcinoma , hypoproteinemia , pathology , anemia , lymph , carcinoma , basal (medicine) , basal cell , insulin
A large basal cell carcinoma, 39 times 26 cm in size, is presented as second in size only to the largest basal cell carcinoma documented (40 times 30 cm), reported by Beck and co‐workers (1). A 61‐year‐old Japanese male visited our clinic with a huge ulcerating tumor on the back. He had hidden the tumor for the previous 30 years. The tumor was histologically confirmed as basal cell carcinoma. The condition was associated with anemia, hypoproteinemia, and dyspnea, and with systemic amyloidosis in the skin, in the lymph nodes, and in the intestinal canal. On admission, the tumor had metastasized to the regional lymph nodes, and, about two years after the first operation, there were metastases to bone and lung, leading to death due to respiratory failure.