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Successful Treatment of Molluscum Contagiosum in the Immunosuppressed Adult with Topical Injection of Streptococcal Preparation OK‐432
Author(s) -
Inui Shigeki,
Asada Hideo,
Yoshikawa Kunihiko
Publication year - 1996
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.1996.tb02667.x
Subject(s) - immunosuppression , molluscum contagiosum , medicine , dermatology , penicillin , chemotherapy , streptococcus pyogenes , antibiotics , surgery , immunology , microbiology and biotechnology , staphylococcus aureus , biology , genetics , bacteria
A 37‐year‐old Japanese woman received an anticancer drug for 5 years following resection of mammary cancer and then developed widespread mollusca contagiosa, which we considered to be caused by immunosuppression induced by the chemotherapy. Because OK‐432 (penicillin‐treated and heat‐treated lyophilized powder of a substrain of Streptococcus pyogenes A ) was expected to be effective for immunosuppression, we tried its topical injection. The skin lesions disappeared almost completely within three months. OK‐432 therapy is considered hopeful for treating viral skin diseases, even in immunosuppressed patients.