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A Case of Secondary Syphilis with Mucous Patches on the Hard Palate
Author(s) -
Ban Masanori,
Ohtani Michihiro,
Seishima Mariko
Publication year - 1995
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.1995.tb03341.x
Subject(s) - syphilis , treponema , medicine , primary syphilis , lesion , pathology , secondary syphilis , serology , dermatology , antibody , immunology , human immunodeficiency virus (hiv)
A rare case of secondary syphilis showing mucous patches on the hard palate is reported. A 31‐year‐old male had two erosive patches which were slightly raised on his hard palate. A linear lesion was also present on the inside of his right alveolar process. Many red‐brown macules on his abdomen and bilateral inguinal lymphadenopathy accompanied these symptoms. The serological tests for syphilis were positive: VDRL test 1:512, TPHA test 1:20,480, and IgM‐FTA‐ABS test 1:40. Immunohistochemical staining with rabbit monoclonal antibody to Treponema pallidum by the biotin‐streptoavidin system detected treponemal organisms in the paraffin‐embedded specimen from his mucous patch. A diagnosis of secondary syphilis was made, and he was given amoxicillin (AMPC) at 750 mg per day for 4 weeks. His eruptions, including the mucous patch, healed in a week.

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