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Nodular Cutaneous Lupus Mucinosis Associated with Atrophie Blanche‐like Lesions in a Patient with Systemic Lupus Erythematosus
Author(s) -
Egawa Hisao,
AbeMatsuura Yoshiko,
Tada Joji,
Arata Jirô
Publication year - 1994
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.1994.tb01815.x
Subject(s) - mucinosis , medicine , pathology , systemic lupus erythematosus , lupus erythematosus , dermatology , disease , antibody , immunology
Background Multiple, pale, atrophic depressions surrounded by erythema developed on nodular cutaneous mucinosis lesions in a patient with systemic lupus erythematosus. Observations A 22‐year‐old man developed multiple nodular erythematous lesions on the upper arms, back, and chest during the course of systemic lupus erythematosus. Histologically, these nodular lesions were diagnosed as lupus mucinosis. Three years later, the patient began to have atrophic depressed lesions on several nodular mucinosis lesions. These lesions did not develop on normal appearing skin. A biopsy specimen from one of these lesions showed occlusion of blood vessels with thickening of their walls and perivascular dense lymphocytic infiltration. No leukocytoclastic vasculitis was found. Hyaline degeneration was present in some parts of the fatty tissue. Conclusion The atrophic depressed lesions were atrophie blanche‐like and induced by the vascular occlusion. Since these lesions developed only on the lupus mucinosis lesions, mucin deposition and vascular changes may be closely related.