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A Statistical Study on In vivo Sorption and Desorption of Water in Ichthyosis Vulgaris
Author(s) -
Mukherjee Soma,
Gupta Amulya Bhusan
Publication year - 1994
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.1994.tb01418.x
Subject(s) - desorption , ichthyosis , sorption , ichthyosis vulgaris , exponential function , conductance , chemistry , physics , mathematics , medicine , dermatology , mathematical analysis , condensed matter physics , adsorption , atopic dermatitis , filaggrin
Experiments on the variation of electrical conductance on sorption and desorption of water were performed on the skin of 34 subjects: 17 ichthyosis vulgaris patients and 17 normal subjects, matched for age and gender, under different ambient conditions. An exponential model of the form f t = θ o e θ t , where f t denotes fractional conductance at time t, describes the process of desorption with high accuracy. The parameter θ , identifiable as the rate of desorption, is significantly different between the ichthyotic and normal populations. The study discusses the impaired barrier function of the ichthyotic skin.