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Sclerotic Fibromas of the Skin
Author(s) -
Nogita Toshitatsu,
Akiyoshi Emiko,
Kawashima Makoto
Publication year - 1991
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.1991.tb03117.x
Subject(s) - enolase , vimentin , fibroma , pathology , lesion , palm , anatomy , medicine , immunohistochemistry , physics , quantum mechanics
We report a case of a 34‐year‐old Japanese woman with a fibrous tumor on the left palm that fulfilled the criteria of sclerotic fibroma of the skin. Immunohistochemically, the tumor cells were positive for vimentin, but negative for S‐100 protein and neuron‐specific enolase. Ultra‐structurally, the cross‐striations of collagen microfibrils were less prominent. Our case supports the concept that sclerotic fibroma of the skin is a distinctive lesion which may represent a hamartoma of the skin.