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Expression of Interleukin 1 in Burn Scars
Author(s) -
Sawada Yukimasa,
Takahashi Masaaki,
Nomura Kazuo
Publication year - 1990
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.1990.tb01690.x
Subject(s) - dermis , scars , epidermis (zoology) , pathology , interleukin , interleukin 1β , medicine , chemistry , dermatology , anatomy , cytokine , immunology
A histochemical study using a Biotin‐Streptavidin procedure for demonstrating interleukin 1 (IL‐1) in burn scar specimens is described. Among seventeen scar specimens, five positive reactions to IL‐1 were observed in the epidermis. No positive reactions in the dermal tissue, however, were detected. The twenty specimens of normal skin used as controls showed no positive reaction in either the dermis or the dermis.