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Cutaneous Metastasis from Hepatocellular Carcinoma Resembling Granuloma Teleangiectaticum
Author(s) -
Yamanishi Kiyofumi,
Kishimoto Saburo,
Hosokawa Yohei,
Yamada Kazuo,
Yasuno Hirokazu
Publication year - 1989
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.1989.tb01593.x
Subject(s) - hepatocellular carcinoma , carcinoembryonic antigen , metastasis , pathology , nodule (geology) , granuloma , immunohistochemistry , carcinoma , medicine , staining , biology , cancer , cancer research , paleontology
We reported a case of cutaneous metastasis originated from hepatocellular carcinoma, which appeared as a nodule resembling granuloma teleangiectaticum. The nodule, which was composed of tumor cells and intervening capillaries, showed characteristics similar to those of primary hepatocellular carcinoma. On immunohistochemical staining, the tumor cells were positive not only for AFP (alpha‐fetoprotein), but also for CEA (carcinoembryonic antigen), which is negative in most cases of primary hepatocellular carcinoma. We discussed this case with a review of previous reports of skin metastasis from liver carcinoma.