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Pigmented Basal Cell Carcinoma Developing on the Lower Extremities
Author(s) -
Ono Tomomichi,
Egawa Kiyofumi,
Yamamoto Shinji,
Arao Tatsuyoshi
Publication year - 1989
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.1989.tb01273.x
Subject(s) - pathology , parenchyma , stroma , basal cell carcinoma , melanosome , melanoma , basal (medicine) , medicine , basal cell , biology , melanin , cancer research , immunohistochemistry , genetics , insulin
Three cases of pigmented basal cell carcinoma were reported which needed to be differentiated from malignant melanoma based on their location and clinical features. Clinicopathologically, they were characterized by a large number of melanophages in the stroma, blockade melanocytes in the parenchyma, and phagocytosis of melanosomes in tumor cells as well as a large number of intraparenchymal melanophages. Two cases were characterized by the aggregation of melanophages in cystic spaces caused by stellate atrophy.