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Paget's Disease of the Male Breast
Author(s) -
Sano Yoshimi,
Inoue Tadanori,
Aso Miki,
Hagari Yoshitaka,
Hattori Kyoko,
Shimao Shuhei,
Notsu Takeshi
Publication year - 1989
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.1989.tb01256.x
Subject(s) - areola , histogenesis , medicine , lymph , modified radical mastectomy , radical mastectomy , axillary lymph nodes , metastasis , axilla , pathology , carcinoma , mammary carcinoma , erythema , breast carcinoma , mastectomy , dermatology , breast cancer , immunohistochemistry , cancer
We report a 61‐year‐old male with mammary Paget's disease. Physical examination revealed a slightly exudative erythema at the areola and a reddish, enlarged left nipple. No tumor or left axillary lymph nodes was palpable. He underwent a left modified radical mastectomy. Histologically, there was an intraductal carcinoma in the upper portion of the mammary ducts. The axillary lymph nodes that were examined were free of metastasis. Paget cells had neither estrogen nor progesterone receptors. We speculated that the histogenesis of Paget cells involved carcinoma cells that invaded the epidermis of the nipple.