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Etretinate Treatment in Disseminated Porokeratosis
Author(s) -
Danno Kiichiro,
Yamamoto Masamitsu,
Yokoo Tadashi,
Ohta Miyuki,
Ohno Sayoko
Publication year - 1988
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.1988.tb04083.x
Subject(s) - porokeratosis , etretinate , parakeratosis , medicine , dermatology , dyskeratosis , hyperkeratosis , psoriasis
A 77‐year‐old man with disseminated superficial porokeratosis of Mibelli (PM) over the whole body surface for 60 years was treated with oral etretinate (1 mg/kg/day) for nine months after resection of two lesions of Bowen's disease. Clinically, hyperkeratotic plaques were flattened after three months of treatment. Histological changes included disappearance of parakeratosis and residual but less stacked cornoid lamella. Etretinate may be the first choice of treatment in widespread porokeratosis.