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A Case of Lichen Sclerosus et Atrophicus of the Vulva Effectively Treated with Oral Etretinate
Author(s) -
Yokota Michiko,
Mizuno Nobuyuki
Publication year - 1988
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.1988.tb03703.x
Subject(s) - etretinate , vulva , medicine , itching , lichen sclerosus , urination , dermatology , surgery , anatomy , urinary system , psoriasis
A 51‐year‐old female had been suffering from itching of the external genitalia and soreness on urination for one year. Swelling, leukokeratosis and erosion on the external genitalia had been seen for six months. Her clinical findings and symptoms improved markedly after eight months administration of oral etretinate (50–10 mg/day, total dose 6,080 mg). Histologically, reappearance of the rete ridges, rearrangement of squamous cells, disappearance of hydropic degeneration of basal cells, dilated lymph capillaries and dense lymphoid cell infiltration in the middermis were prominent findings after treatment.