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Effects of PSK Ointment and OK‐432 Ointment of Pseudomonas Burn Wound Infection in Mice
Author(s) -
Watanabe Takashi,
Saito Hajime
Publication year - 1987
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.1987.tb03591.x
Subject(s) - pseudomonas aeruginosa , burn wound , microbiology and biotechnology , streptococcus pyogenes , pseudomonas , wound healing , bacteria , inoculation , streptococcus , polysaccharide , chemistry , medicine , biology , immunology , staphylococcus aureus , biochemistry , genetics
When Pseudomonas aeruginosa was inoculated onto wound surfaces of burned mice, PSK ointment consisting of Solbase and PSK (a protein‐bound polysaccharide from Coriolus versicolor ) and OK‐432 ointment consisting of Solbase and OK‐432 (an attenuated Streptococcus pyogenes Su) enhanced the clearance of Pseudomonas aeruginosa , and promoted the healing of the burn wounds. Bacteria‐eliminating and wound‐healing effects of these ointments were much the same or somewhat better than those of commercially available ointments such as Geben (Silvadene) and Mafatate (Sulfamylon) creams.