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Amikacin Treatment for Mycobacterium Marinum Infection
Author(s) -
Arai Hiroko,
Nakajima Hiroshi,
Naito Shizuo,
Kaminaga Yoichiro,
Nagai Ryukichi
Publication year - 1986
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.1986.tb02960.x
Subject(s) - mycobacterium marinum , amikacin , microbiology and biotechnology , medicine , erythema , antibiotics , lesion , biology , mycobacterium , surgery , pathology , tuberculosis
This report describes a case of Mycobacterium marinum skin infection. A granulomatous plaque on the dorsum of the left hand of a 71‐year‐old man who kept a tank of tropical fish was followed by erythema and induration on the left forearm of the lymphocutaneous type. The lesion was successfully treated with 6 weeks of administration of amikacin (28 intramuscular injections) a total of 3500 mg. The isolated M. marinum strain was sensitive in vitro to amikacin at 0.78 μ g/ml. Furthermore, another 15 clinical strains of M. marinum showed high sensitivity in vitro to this drug (93% of the 16 strains were sensitive to between 0.78 and 1.56 μ g/ml).