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VERRUCIFORM XANTHOMA OF THE SCROTUM
Author(s) -
Shindo Yasuko,
Mikoshiba Hajime,
Okamoto Kikuhiko,
Morohashi Masaaki
Publication year - 1985
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.1985.tb02870.x
Subject(s) - xanthoma , dermis , scrotum , pathology , lesion , infiltration (hvac) , epidermis (zoology) , papillary dermis , anatomy , chemistry , medicine , materials science , composite material
We report two cases of verruciform xanthoma of the scrotal skin. In each case, the tumor was a single pink lesion with firm consistency and a granular surface. Each lesion was characterized histopathologically by papillomatous proliferation of the epidermis and dermis and dense foam‐cell infiltration of the region corresponding to the dermal papillary layer. These cells proved to be xanthoma cells that stained negatively or weakly positively with PAS, colloidal iron, and Alcian blue and strongly positively with Sudan III. No medical problems were found in either patient, and serum lipid levels were normal. This report also presents electron microscopic findings from scrotal verruciform xanthoma in one case and the results of lipid analysis of tumor tissue from both cases.