Premium
THE ADHESION OF STAPHYLOCOCCUS EPIDERMIDIS TO CULTURED CELLS
Author(s) -
Kawashima Takeshi
Publication year - 1985
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.1985.tb02845.x
Subject(s) - staphylococcus epidermidis , microbiology and biotechnology , staphylococcus aureus , fibronectin , adhesion , micrococcus luteus , bacteria , biology , chemistry , cell , biochemistry , organic chemistry , genetics
In this study, the author observed the adhesion of Staphylococcus (St.) epidermidis to three kinds of cultured cells—human epidermal cells (JTC‐17), human synovial cells (McCoy) and mouse connective tissue cells (L). In the same manner, St. aureus, Micrococcus (M.) luteus and Pseudomonus (Ps.) aeruginosa adhered to the cells, but Escherichia (E.) coli did not. Heat killing M. luteus decreased its adhesiveness, and heat killing Ps. aeruginosa eliminated its ability, but the adhesion of Staphylococci was not altered by the heat treatment. The adhesiveness of living bacteria was also evaluated by a colony forming unit (CFU) counting study. St. epidermidis adhered to the same extent as St. aureus , which is reported to adhere to epithelial cells through fibronectin. Human plasma fibronectin (Fn) treatment inhibited the adhesiveness of St. epidermidis to JTC‐17 cells. This suggests that St. epidermidis may have a receptor for Fn as St. aureus does.