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DRUGS CAUSING FIXED ERUPTIONS
Author(s) -
Kanwar A.J.,
Belhaj M.S.,
Bharija S.C.,
Mohammed Mohgat
Publication year - 1984
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.1984.tb01492.x
Subject(s) - oxyphenbutazone , phenylbutazone , metamizole , provocation test , drug , medicine , ibuprofen , dermatology , pharmacology , analgesic , pathology , alternative medicine
Seventy one patients having fixed drug eruptions were subjected to provocation tests. The greatest number of cases were due to acetylsalicylic acid (18). Other drugs responsible were hyposcine butylbromide (15), oxyphenbutazone (14), sulphadiazine (7), tetracycline hydrochloride (6), metamizole (5) and ibuprofen (3). Other drugs were less frequent. There was evidence of cross sensitivity between various tetracyclines and sulphonamides and also between oxyphenbutazone and phenylbutazone. One patient had two groups of lesions, each reacting to a different, chemically unrelated drug.