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EFFECTS OF SERUM ALBUMIN ON COAGULASE RELEASE FROM STAPHYLOCOCCUS AUREUS DERIVED FROM BULLOUS IMPETIGO
Author(s) -
Dekio Satoshi,
Jidoi Joji
Publication year - 1984
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.1984.tb01471.x
Subject(s) - coagulase , staphylococcus aureus , impetigo , microbiology and biotechnology , albumin , titer , chemistry , staphylococcus , serum albumin , fibrin , immunology , bacteria , medicine , biology , antibody , biochemistry , genetics
Three strains of Staphylococcus aureus derived from bullous impetigo were cultured in media either not containing or containing serum albumin. The coagulase titers in each medium were measured as a function of the cultivation time. In the early‐mid phase of growth, the coagulase titers were increased to the same degree in both media. After that, the coagulase titers were maintained at the high level in the medium containing serum albumin but decreased in the medium not containing serum albumin. It is proposed that Staphylococcus aureus strains capable of causing bullous impetigo infect the injured skin surface with accumulation of plasma‐like material, and then grow with continuous release of coagulase. Under the protection of the fibrin membranes formed by the coagulase, the bacteria are established, and then the bullous lesions are formed.