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A CASE OF STEWART‐TREVES SYNDROME
Author(s) -
Setoyama Mitsuru,
Mera Shuji,
Nomoto Shigeru,
Tashiro MasaAki
Publication year - 1984
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.1984.tb01445.x
Subject(s) - pathology , dermis , angiosarcoma , eosinophilic , immunohistochemistry , cytoplasm , lymphatic system , reticular dermis , anatomy , biology , medicine , microbiology and biotechnology
A case of so‐called postmastectomy lymphangiosarcoma occurring 14 years after radical mastectomy and radiation therapy for the left mammary carcinoma was studied histologically, electron‐microscopically and immunohistochemically. The tumor cells formed cellular areas in the deeper dermis and vascular areas in the upper dermis. The tumor cells had round to spindle‐shaped hyperchromatic nuclei and poorly delineated eosinophilic cytoplasm. In an immunohistochemical study for factor VIII relating antigen (F VIII RAG), positive staining was observed in the cytoplasm of some atypical tumor cells lining vascular channels and in that of a few tumor cells in cellular areas. Electron‐microscopically, the tumor cells were similar to vascular endothelial cells. In these studies, this tumor appeared to mimic not only lymphatic vessels, but also blood vessels. For these reasons, the authors propose that the term “angiosarcoma” would be better suited than “lymphangiosarcoma”.