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LABORATORY STUDY OF COLLAGEN WOUND DRESSING (CAS)
Author(s) -
Takeda Ueto,
Izawa Masanori,
Koeda Takemi,
Shibata Uichi
Publication year - 1983
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.1983.tb01185.x
Subject(s) - antigenicity , immunogenicity , wound healing , chemistry , antibody , medicine , immunology
In order to determine whether collagen wound dressing (CAS) has any immunogenicity, we carried out various immunological tests with Japanese albino rabbits and BALB/c mice. CAS extract produced no antibodies while atelocollagen, the source material of CAS, has less antigenicity than acid soluble collagen, a tropocollagen. Moreover, the antigenicity of CAS was much lower than that of lyophilized porcine skin which is much used in clinical practice. It is assumed that CAS would be immunologically safe as a wound dressing.