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POLYMORPHIC TYPE OF XANTHOMATOSIS IN ASSOCIATION WITH IgA MYELOMA
Author(s) -
Hagiyama Masaharu,
Arima Terukatsu,
Arata Jiro,
Namba Koji,
Murakami Motoo,
Inamizu Mariko,
Nishimoto Masayoshi
Publication year - 1982
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.1982.tb01073.x
Subject(s) - xanthoma , multiple myeloma , medicine , pathology , bone marrow , plasma cell
Clinical and immunochemical findings were reported from a 36‐year‐old woman with multiple xanthomas of various clinical types (plane xanthoma, tubero‐tendinous, papulo‐eruptive and follicular xanthomas), multiple myeloma (IgA, type L), and hyperlipemia with markedly elevated levels of plasma cholesterol and triglycerides. A bone marrow specimen showed foam cells and atypical plasma cell proliferation. Lipoprotein‐IgA complexes were thought to exist in the serum of this patient on gel filtration and micro‐ouchterlony test. Cutaneous xanthomas associated with multiple myeloma are plane xanthomas in most of the reported cases. Combination of several different types of xanthomas has been reported in only three cases, all of which were associated with IgA myeloma.