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LYMPHOCYTE STUDIES IN BULLOUS PEMPHIGOID
Author(s) -
Ahmed A. Razzaque
Publication year - 1981
Publication title -
the journal of dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.9
H-Index - 65
eISSN - 1346-8138
pISSN - 0385-2407
DOI - 10.1111/j.1346-8138.1981.tb02589.x
Subject(s) - bullous pemphigoid , pemphigoid , medicine , peripheral blood , stimulation , receptor , lymphocyte , immunology , antibody
ABSTRACT Lymphocyte studies were performed on 19 untreated patients with active bullous pemphigoid and 35 controls. Peripheral blood T cells, Fc receptor‐bearing cells, B cells and phytohemag‐glutinin (PHA) stimulation were studied. Patients with bullous pemphigoid did not have statistically significant levels of circulating T cells, B cells, or Fc receptor‐bearing cells, compared to normals (P≥0.05). PHA stimulation was significantly lower in bullous pemphigoid patients, P values being 0.006, 0.007 and 0.008 at PHA concentration of 1/2,500, 1/1,000, and 1/100 respectively. This study demonstrates that one of the functions of T cells in the peripheral blood leukocytes from patients with bullous pemphigoid is decreased.